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photoactivatable fluorescent protein : ウィキペディア英語版
photoactivatable fluorescent protein
Photoactivatable fluorescent proteins (PAFPs) exhibit fluorescence that can be modified by a light-induced chemical reaction.
== History ==

The first PAFP, Kaede (protein), was isolated from ''Trachyphyllia geoffroyi'' in a cDNA library screen designed to identify new fluorescent proteins.〔Ando ''et al.'' 2002 ''PNAS'' 99(20) pp 12651-6.〕 A fluorescent green protein derived from this screen was serendipitously discovered to have sensitivity to ultraviolet light--

We happened to leave one of the protein aliquots on the laboratory bench overnight. The next day, we found that the protein sample on the bench had turned red, whereas the others that were kept in a paper box remained green. Although the sky had been partly cloudy, the red sample had been exposed to sunlight through the south-facing windows.〔Ando et al. 2002 PNAS 99(20) p 12652〕


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